European travel itinerary across multiple cities
Europe Itinerary

2-Week Europe Hotel Itinerary

Published October 30, 2024

2026 · 2 min read Multi-Destination Trips Editorial Team

A 2-week European itinerary works best across 3 destinations of distinct character. The framework below covers three working combinations.

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The three working combinations

Combination 1: Paris + Italy + Greece

Days 1-4: Paris (Le Bristol or The Ritz Paris) Days 5-9: Amalfi Coast (Le Sirenuse) Days 10-14: Santorini (Canaves Oia Epitome)

Best for: cultural + romantic + cliffside variety.

Combination 2: London + Italy + South France

Days 1-4: London (The Connaught or Claridge's) Days 5-9: Tuscany (Castiglion del Bosco) Days 10-14: French Riviera (Hotel du Cap-Eden-Roc)

Best for: heritage + countryside + coastal luxury.

Combination 3: Spain + Italy

Days 1-5: Barcelona (Mandarin Oriental Barcelona) Days 6-10: Florence (Helvetia & Bristol) Days 11-14: Amalfi Coast (Belmond Hotel Caruso)

Best for: Mediterranean cultural depth.

Practical advice

Three points:

Train infrastructure

European rail is exceptional. Train between Italy + France + Spain rather than flying.

Restaurant reservations

Pre-book major restaurants in each city 4-6 weeks ahead.

Hotel transfers

Use hotel-arranged transfers in unfamiliar cities; use trains between cities.

Five rules

  1. 2 weeks supports 3 destinations comfortably
  2. Front-load the longest flight (transatlantic to start)
  3. Trains between European destinations beat flights
  4. Match destination character to trip rhythm (active + cultural + relaxing)
  5. End in a relaxing destination

For more, see the multi-destination pillar.

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